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多西他赛联合顺铂治疗晚期乳腺癌22例疗效分析

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摘要 目的:观察多西他赛联合顺铂治疗晚期乳腺癌疗效及不良反应。方法:22例晚期乳腺癌采用多西他赛35mg/m^2,静脉滴注1小时,d1、d8,化疗前一天给予地塞米松7.5mg,日2次,连用3天。顺铂20mg/m^2,静脉滴注d1~5。21天为1周期,至少应用2个周期后评价疗效,按照WHO标准进行评价。结果:晚期乳腺癌22例中完全缓解(CR)3例,部分缓解(PR)11例,稳定(SD)5例,进展(PD)3例。总有效率(PR+CR)为63.6%。初治疗效结果显示高于复治。结论:多西他赛联合顺铂治疗晚期乳腺癌疗效确切,不良反应可以耐受,可推广应用。
作者 王仲涛
出处 《中国民康医学》 2008年第13期1433-1434,共2页 Medical Journal of Chinese People’s Health
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