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肾细胞癌p16基因缺失与预后的关系 被引量:2

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摘要 肾细胞癌p16基因缺失与预后的关系赵坡钟梅许红民吕亚利陈乐真一、材料与方法1.标本:31例肾细胞癌取自解放军总医院病理科1960~1985年存档的福马林固定、石蜡包埋组织标本,其中透明细胞癌20例,颗粒细胞癌5例,混合细胞癌6例;按分化程度有高分化癌...
出处 《中华病理学杂志》 CAS CSCD 北大核心 1997年第5期310-310,共1页 Chinese Journal of Pathology
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同被引文献11

  • 1李楠.p16基因与肿瘤[J].国外医学(肿瘤学分册),1995,22(5):257-259. 被引量:17
  • 2Moulton T,Samara G,Chung W,et al.MTS1/CDKN2 lesion in primary glioblastoma multiforme[J].Am J Pathol,1995,146:613.
  • 3Schmidt EE,Ichimura K,Reifenberger G,et al.CDKN2(p16MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas[J].Cancer Res,1994,54:6321.
  • 4Izumoto S,Arita N,Ohnishi T,et al.Homozygous deletions of p16/MTS1 and p15/MTS2 genes in glioma cells and primary glioma tissues[J].Cancer Lett,1995,97:241.
  • 5Giani C,Tinociaro G.Mutation rate of CDKN2 gene in malignant gliomas[J].Cancer Res,1994,54:6338.
  • 6Tenan M,Benedetti S,Finocchiaro G.Deletion and transfection analysis of the p15/MTS2 gene in malignant gliomas[J].Biochem Biophys Res Commun,1995,217(1):195-202.
  • 7Serrano M,Hanno DJ,Beach D.A new regulatory motif in cell cycle control causing specific inhibition of cyclin-CDK4[J].Nature,1993,366:704.
  • 8Kamb A,Gruis NA,Weaver-Feldhaus J,et al.A cell cycle regulator potentially invoved in genes of many tumor types[J].Science,1994,264:436.
  • 9Ueki K,Robio MP,Ramesh V,et al.MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p[J].Hum Mol Genet,1994,3:1841.
  • 10Hayashi Y,Yamashita J,Yamaguchi Y.Timing and role of p53 gene mutation in the recurrence of gliomas[J].Biochem Biophys Res Commun,1991,180(2):1145.

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