102例阿尔茨海默病人的血脂水平分析

Analysis of Serum Lipid Level in 102 Cases of Alzheimer.

目的:对阿尔茨海默病人血脂进行测定和分析,了解其血脂与同年龄段健康人是否存在差异。方法:选择102例病例和86例同年龄段正常对照,测定血清总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(ApoA1)及载脂蛋白B(ApoB)等六项血脂指标,并将病例样本与同年龄组正常人进行比较研究。结果:102例病例样本与86例正常对照比较,TC、LDL-C、ApoB升高,ApoA1降低,有显著性差异(P<0.05),TG、HDL-C无显著性差异(P>0.05)。结论:阿尔茨海默病人与同年龄段健康人之间存在血脂水平的差异。

Objective：Through analyzing the serum lipid level to understand whether there are some differences between Alzheimer＇ s patients and the same age healthy individuals. Methods：We measured levels of cholesterol （ TC）, triglyeeride （ TG）, HDL-cholesterol （HDL-c）, LDL-cholesterol （LDL-c）, apolipoproteinA1 （ApoA1） and apolipoproteinB （ApoB） in 102 AD patients and 86 the same age healthy individuals and compared them between the two groups. Results： Compared with the same age healthy individuals group, for 102 Alzheimer＇ s patients group, the levels of TC, LDL-c and ApoB were higher （ P 〈 0.05） , and ApoAI was lower （ P 〈 0.05）. There were not significant differences in TG and HDL-c （ P 〉 0.05 ）. Conclusions：There are differences in serum lipid level between Alzheimer＇ s patients and the same age healthy individuals.