大肠癌术中经门静脉系统灌注化疗药预防肝转移疗效分析
摘要
目的:探讨大肠癌根治术后预防肝转移的方法。方法:将100例大肠癌患者随机分成两组,实验组在术中经门静脉系统灌注多种化疗药物,其余治疗与对照组相同。结果:经随访2 a,试验组肝转移率14%,对照组32%。有统计学差异。结论:大肠癌术中经门静脉系统灌注多种化疗药对预防肝转移有显著意义。
出处
《中国误诊学杂志》
CAS
2008年第22期5362-5363,共2页
Chinese Journal of Misdiagnostics
参考文献3
-
1曲天勇,王明辉,刘恩卿,马凯.大肠癌根治术后静脉系统置管化疗预防肝转移[J].中国冶金工业医学杂志,1999,16(2):97-98. 被引量:1
-
2阚和平,田伏洲,周庆贤,刘晓波,李小军.免疫治疗预防大肠癌术后肝转移[J].中国普通外科杂志,2001,10(3):234-236. 被引量:4
-
3杨玉波,张强,潘克勤.门静脉5—Fu化疗预防大肠癌肝转移的临床应用现状[J].实用肿瘤学杂志,2000,14(2):157-159. 被引量:3
二级参考文献22
-
1喻德.现代肛肠外科学[M].北京:人民军医出版社出版,1997.428.
-
2[1]Weber SM, Jarnagin WR, DeMatteo RP, et al. Survival after resection of multiple hepatic colorectal metsases[J]. Ann Surg Oncol, 2000,7(9):643-650.
-
3[2]Asbun HJ, Hugher KS. Management of recurrent and metastatic colorectal carcinoma[J]. Surg Clin North Am, 1993,73(1):145-166.
-
4[3]Schiltz PM, Beutel LD, Nayak SK, et al. Characterization of tumor-infiltrating lymphocytes derived from human tumors for use as adoptive immunotherapy of cancer[J]. J Immunother, 1997,20(5):377-386.
-
5[4]Pockaj BA, Sherry RM, Wei JP, et al. Localization of indium labeled TIL to tumor in patient receiving adoptive immunotherapy: augmentation with cyclophosphamide and correlation with response[J]. Cancer,1994,73(6):1731-1737.
-
6[5]Ikarashi H, Fujita K, Takakuwa K, et al. Immunomodulation in patients with epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes[J]. Cancer Res, 1994,54(1):190-196.
-
7[6]Kradin RL, Lazarus DS, Dubinett SM, et al. Tumor-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer[J]. Lancet,1989,18(1):577-580.
-
8[7]Bukowski RM, Sharfman W, Murthy S, et al. Clinical results and characterization of tumor-infiltrating lymphocytes with or without recombinant interleukin 2 in human metastatic renal cell carcinoma[J]. Cancer Res, 1991,51(16):4199-4205.
-
9WereldsmaJC,BrugginkED,MeijerWS,etal.Adjuvantportalliverinfusionincolorectalcancerwith5-fluorouracil/heparinversusurokinaseversuscontrol.Cancer1990;65:425
-
10WolmarkN,RocketteH,WickerhamDL,etal.AdjuvanttherapyofDukes'A,B,andCadenocarcinomaofthecolonwithportorveinfluorouracilhepaticinfusion:preliminaryresultsofnationalSurgicalAdjuvantBreastandBowelProjectProtocolC-02.JChinOncol1990;8:1466
共引文献5
-
1黄炯强,雷建,胡明,郑文博.门静脉持续化疗联合腹腔大容积化疗预防大肠癌术后肝转移的研究[J].现代临床医学生物工程学杂志,2005,11(4):283-284.
-
2凌伟,颜亚平,李良月.结直肠癌预后影响因素分析:附112例报告[J].中国普通外科杂志,2007,16(9):923-925. 被引量:12
-
3李振洪,李立志,陈利生.结直肠癌肝转移的治疗进展[J].结直肠肛门外科,2007,13(1):56-59. 被引量:1
-
4曹志宇,蒲永东,何建苗,杨波,董立国,朱志东.大肠癌根治术后门静脉置泵化疗预防肝转移[J].解放军医学杂志,2002,27(4):355-356. 被引量:2
-
5李群,胡卫红,李鹏,冯涛.胃癌腹腔热低渗液灌注及门静脉化疗[J].中华外科杂志,2002,40(11):877-877. 被引量:2
-
1董建国,刘献福,任选义.两种药物灌注预防浅表性膀胱癌术后复发的疗效对比[J].中国实用医药,2009,4(9):85-86. 被引量:1
-
2沈建斌,莫子庚,邓亚平.乳腺癌术中局部热疗加化疗的疗效观察[J].中国普通外科杂志,2003,12(10):795-796.
-
3杨连升,张学忠,高红宣,李昌林,赵金全.吡柔比星膀胱灌注预防膀胱癌术后复发的临床研究[J].肿瘤研究与临床,2007,19(8):549-550.
-
4卓文利,谭建明,陆晓哲.经尿道膀胱肿瘤切除联合术后膀胱灌注吡柔比星治疗浅表性膀胱肿瘤[J].医学临床研究,2008,25(7):1186-1188. 被引量:7
-
5严宏.经腹股沟淋巴结灌注化疗药的临床观察(附41例报告)[J].福建医药杂志,1997,19(4):32-33. 被引量:1
-
6梁秦龙,李树业,安媛.头颈部恶性肿瘤综合治疗探讨[J].陕西肿瘤医学,2000,8(3):148-149. 被引量:2
-
7许剑民,钟芸诗,牛伟新,任黎,赖衍翰,王建华,颜志平,程洁敏,秦新裕.术前肝动脉联合区域动脉灌注化疗预防结直肠癌术后肝转移[J].中华医学杂志,2006,86(2):88-92. 被引量:20
-
8马红芳,于千.吡柔比星膀胱灌注预防膀胱癌术后复发53例分析[J].中国误诊学杂志,2009,9(31):7707-7707.
-
9田春英.原发性肝癌53例肝动脉灌注化疗栓塞术后的护理[J].慢性病学杂志,2010,12(11):1505-1506.
-
10王军,宣小华,袁庆鑫,付庆江.姑息手术加区域灌注化疗治疗晚期胰头癌[J].实用肿瘤杂志,2005,20(5):443-444.