成都市357例6月～6岁儿童铁缺乏症的流行病学调查

EPIDEMIOLOGICAL INVESTIGATION ON THE IRON DEFICIENCY IN 357 CHILDREN AT THE AGE OF 6 MONTHS TO 6 YEARS IN CHENGDU

[目的]调查成都市6月～6岁儿童铁缺乏症的患病率。[方法]流行病学调查采用的是系列样本的方法,选取来我院调查的357例6月～6岁的健康儿童。利用HITACHI7600-010全自动生化分析仪(日本)检测转铁蛋白饱和度TfS,全血自动血细胞分析仪(XE-2100,Sysmex,日本)检测血红蛋白。[结果]6个月～6岁儿童IDE患病率为16.53%、IDA患病率为4.76%、铁缺乏症患病率为21.29%;6～12个月儿童IDE患病率为23.08%、IDA患病率为23.08%、铁缺乏症患病率为46.16%;13～36个月儿童IDE患病率为19.73%、IDA患病率为2.72%、铁缺乏症患病率为22.45%;37个月～6岁儿童IDE患病率为11.39%、IDA患病率为0.63%、铁缺乏症患病率为21.29%。不同年龄组儿童IDE、IDA、铁缺乏症患病率由高到低依次为6～12个月(婴儿组),13～36个月(幼儿组),37个月～6岁(学前组),各年龄组差异有统计学意义(P﹤0.05)。不同性别儿童患病率比较差异无统计学意义(P﹥0.05)。[结论]婴儿组、幼儿组铁缺乏症患病率最高,不同年龄组儿童IDE患病率均明显高于IDA患病率,说明隐性缺铁已成为营养性铁缺乏症的主要问题。成都市应根据自己区域的铁缺乏症患病率,制定相应的儿童发展规划。

[Objective] To investigate the prevalence of children with iron deficiency at the age of 6 months to 6 years in Chengdu [ Methods] 357 Children at the age of 6 months to 6 years were randomly selected by using serial sampling method. TfS saturation of transferrin was detected by HITACHI 7600-010 automatic biochemistry analyzer （Japan）, and the hemoglobin was also detected with whole blood automatic cytoanalyze （Sysmex XE-2100）. [Results] The morbidities of iron deficient erythropoiesis （IDE）, iron deficiency anemia （IDA） and iron deficiency for children at the age of 6 months to 6 years were 16.53%, 4.76% and 21.29%, respectively, for children at the age of 6 months to 12 months were 23.08%, 23.08% and 46.16%, respectively, for children at the age of 13 months to 36 months were 19.73%, 2.72% and 22.45%, respectively, and for children at the age of 37 months to 6 years were 11.39%, 0.63% and 21.29%, respectively. The incidences of IDE, IDA and iron deficiency was in a decreasing order as follows： children at the age of 6 months to 12 months （infant group）, children at the age of 13 months to 36 months （young children group） and children at the age of 37 months to 6 years （preschool children）, furthermore, significantly difference were found among the three groups （P 〈 0.05）. [Conclusion] Children in infant group and young children group bad the highest morbidity of iron deficiency. The morbidities of IDE in all groups were significantly higher than the morbidities of IDA, which demonstrated that inapparent ID had become the main nutritional ID for children. The govemment of Chengdu should make related development planning for Children according to morbidity of iron deficiency in children of Chengdu.