苯偶酰的高效简便合成

Convenient and Efficient Synthesis of Benzi

以Fe3+/Cu2+为氧化剂,绿色氧化苯偶姻合成了苯偶酰,研究了铜盐、铵盐和硝酸盐的类型及其用量对反应的影响,讨论了可能的反应的机理.结果表明:以10 mmol苯偶姻为原料,2 mL 2%的Cu(OAc)2溶液为氧化剂,10 mmol硝酸铵为助剂,14 mL冰醋酸为溶剂,添加1 g FeCl3.6H2O,回流温度下反应时间可从90 min减少至60 min,苯偶酰的收率高达98.4%,其结构经红外光谱、元素分析等进行了表征.

Benzi was green synthesized from benzoin with Fe^3＋/Cu^2＋ as oxidation, and its structure was characterized by IR and EA. The effect of copper compounds, ammonium salt, nitrates and their mass were studied, the proper reaction mechanism was discussed, and the optimum conditions were obtained as follows： the yield was as high as 98.4% when benzoin was 10 mmol, 2% copper acetate 4mL, ammonium nitrate 10 mmol, glacialacetic acid 14 mL , and the mixture was then refluxed. If 1 g FeCl3·6H2O was added, the reaction time was reduced from 90 min to 60 min.