摘要
PSD是最早在电镜下发现的位于突触后膜的“致密物蛋白质”。这种“致密物”是由一系列细胞骨架蛋白结合了多种与突触信号传递相关的分子（包括受体和各种激酶等）构成的特殊结构。其中一些成员，包括NMDA受体、CaMKII、PSD-93及PSD-95，与疼痛的发生、维持及治疗密切相关，并且彼此之间有着“微妙”的相互调节作用。
Postsynaptic density （PSD） is a kind of ‘density＇ which is visible in the electron microscope at the postsynaptic membrane. The ‘density＇ includes a lot of receptors and kinases binding on some scaffold proteins. Amang of PSD, NMDA receptor, CaMKIII, PSD -93 and PSD -95 may play an important role in pain occurrence, maintenance and management, themself may have the ‘ delicacy＇ modulation on each other.
出处
《国际麻醉学与复苏杂志》
CAS
2008年第3期244-247,共4页
International Journal of Anesthesiology and Resuscitation
