穴位注射结合抗抑郁药物治疗抑郁症的临床观察

Clinical Observations on Treatment of Depression by Point Injection plus Antidepressants

目的观察穴位注射结合抗抑郁药物治疗抑郁症的临床疗效和副反应情况,评价其应用价值。方法100例抑郁症患者随机分为两组,每组50例。药物组服用5-羟色胺重摄取抑制剂(SSRIs)类抗抑郁药帕罗西汀20mg,每日1次,连续治疗3个月;针药组应用穴位注射治疗,同时服用SSRIs类抗抑郁药帕罗西汀,服法同前,连续治疗3个月。治疗前后分别进行汉密尔顿抑郁量表(HAMD)测定,治疗后进行副反应量表(TESS)测定,以HAMD减分率作为疗效评定指标,TESS评定副反应情况。结果针药组起效更快,疗效优于药物组,副反应较药物组少。结论穴位注射结合抗抑郁药物治疗抑郁症起效快,副反应少。

Objective To investigate the clinical efficacy and side effects of point injection plus antidepressants in treating depression and evaluate its application value.Methods One hundred depression patients were randomly allocated to two groups,50 cases each.The medicine group was treated with Paroxetine,an antidepressant in the selective serotonin reuptake inhibitor（SSRIs）class,20mg once daily for three consecutive months.The acupuncture-medicine group was treated by point injection and administration of Paroxetine in the same way as the above,for three consecutive months.The Hamilton Depression Scale（HAMD）was applied before and after treatment and the Treatment Emergent Symptom Scale（TESS）,after treatment.The reduction rate in HAMD score was used as an index for the evaluation of therapeutic effects.The adverse responses were evaluated by TESS.Results The therapeutic effect occurred more quickly and was better and the side effects were fewer in the acupuncture-medicine group than in the medicine group.Conclusion Point injection plus antidepressants produces a quick therapeutic effect and few side effects in treating depression.