胰岛素注射液对注射用头孢地嗪钠稳定性的影响

Effect of Insulin Injection on the Stability of Cefodizime Sodium for Injection

目的:考察胰岛素注射液在5%葡萄糖注射液中对注射用头孢地嗪钠稳定性的影响。方法:考察配伍液在12h内的外观及pH值变化,采用高效液相色谱法测定头孢地嗪钠的含量。结果:配伍液在室温下12h内无明显外观、pH值、含量变化。结论:胰岛素注射液在室温下12h内对头孢地嗪钠稳定性无影响。

OBJECTIVE： To study the effect of insulin injection on the stability of cefodizime sodium for injection in 5% glucose injection. METHODS： The appearance and the pH value of the mixed solution in 12 h were monitored and the content of cefodizime sodium in the mixed solution was determined by HPLC. RESULTS： There were no evident changes for the mixture in appearance, pH value and the content of cefodizime sodium within 12 h at room temperature. CONCLUSION： Insulin injection has no effect on the stability of cefodizime sodium within 12 h at room temperature.