我院2006年93例药品不良反应报告分析

ADR Reports:Analysis of 93 Cases in Our Hospital

目的：方法：了解我院药品不良反应（ADR）发生的一般规律及特点。方法：对我院2006年1月1日～12月31日收集的93例ADR报告，分别从报告人、患者性别与年龄分布、药品种类、给药途径、涉及器官或系统及临床表现等方面进行统计、分析。结果：93例ADR报告中，〉60a的患者ADR发生率最高（占47．3％），涉及药品以抗感染药居多（占31.2％），静脉给药方式是引发ADR的重要给药途径（占69．9％），ADR最常见的临床表现为皮肤及其附件损害（占35．5％）。结论：应合理使用抗感染药，避免或减少ADR的发生。

OBJECTIVE： To study the regular pattern and characteristics of adverse drug reactions （ADR） in our hospital. METHDOS： 93 ADR cases collected from Jan. 1, 2006 to Dec. 31, 2006 in our hospital were analyzed statistically in respect of drug categories ,Sex and age distribution, routes of administration, organs and systems involved and clinical manifestations etc. RESULTS： Of the 93 ADR cases, the patients aged above 60 showed the highest proportion （47.3%） ; 31.2% were induced by anti-infective drugs; 69.9% were induced through intravenous way; and damages of skin and its appendants were the most common manifestations （35.5%） . CONCLUSION： Anti infective drugs should be used rationally to avoid or reduce the occurrence of ADR.