认知干预对鼻咽癌患者治疗后性功能的影响

Effects of Cognitive Intervention on Sexual Function in Patients with Nasopharyngeal Carcinoma after Treatment

[目的]探讨认知干预对鼻咽癌(NPC)患者性功能的影响。[方法]31例新入院的NPC患者作为干预组,在治疗前进行认知干预,40例来院复查的NPC患者作为对照组,分别采用O’Leary(1995)男性性功能问卷和女性性功能指数(FSFI)量表评估患者治疗前及治疗结束3个月至1年内的性功能状况。[结果]治疗前后男性性功能总分及性欲、勃起、射精、知觉和满意度得分在干预组分别为30.59±1.23和31.74±1.62、2.04±0.12和1.77±0.17、8.93±3.59和9.37±0.61、6.96±0.23和6.81±0.35、7.85±0.64和8.85±0.70、3.07±0.16和3.15±0.18,对照组为37.89±0.65和30.02±1.32,2.14±0.16和1.50±0.18、11.53±0.21和10.69±0.49、7.83±0.01和4.50±0.63、11.06±0.43和10.75±0.49、3.64±0.11和1.083±0.29,干预组总分在治疗前后变化无统计学意义(P=0.392),但在对照组却有统计学意义的下降(P=0.008)。[结论]认知干预保护了NPC患者治疗后的性功能,有一定的临床价值。

[Purpose ] To explore the effects of cognitive intervention on sexual function in patients with nasopharyngeal carcinoma （NPC） after treatment. [Methods ] Thirty-one new inpatients with NPC received cognitive interventions before treatment were enrolled as intervention group and 40 follow-up cases with NPC were enrolled as control group. All patients＇ sexual function were assessed before treatment and between 3 months to 1 year after treatment by O＇Leary （1995） Brief Male Sexual Function Inventory Scale for male patients and Female Sexual Function Index （FSFI） for female patients. [Results ] The total score and score of sexual desire, erection, ejaculation, perception, satisfaction of male patients in pre-and post-treatment were 30.59±1.23 and 31.74±1.62, 2.04±0.12 and 1.77±0.17, 8.93±0.59 and 9.37±0.61, 6.96±0.23 and 6.81±0.35, 7.85±0.64 and 8.85±0.70, 3.07±0.16 and 3.15±0.18 in intervention group; and in control group which were 37.89±0.65 and 30.02±1.32, 2.14±0.16 and 1.50±0.18, 11.53±0.21 and 10.69±0.49, 7.83±0.01 and 4.50±0.63, 11.06±0.43 and 10.75±0.49, 3.64±0.11 and 1.083±0.29. There was no statistically significance of pre-and post-treatment total score in intervention group （P=0.392）, but the total score in control group decreased with statistically significance （P=0.008）. [Conclusion] Cognitive intervention plays a protecting role for sexual function in patients with NPC after treatment. It is valuable in clinical application.