OSAS患者体重指数与呼吸暂停低通气等指标的相关性研究

The Association of Apnea-hypopnea Indices with Body Mass Index in Patients with OSAS

目的探讨阻塞性睡眠呼吸综合征（OSAS）患者体重指数（BMI）与呼吸暂行低通气指数（AHI）等有关指标的相关性。方法将57例睡眠初筛检查诊断为OSAS患者的数据按BMI≤23．9、24～27．9、≥28排序分组，用SPSS12．0版统计软件进行t检验和相关性分析。结果除AHI和鼾声指数与BMI呈明显相关外，其余所选指标与BMI皆无显著相关，但组间比较除AHI未见显著差异（P〉0．05）外，其余指标呈组间两相比较或至少其中两组组间比较存在显著差异（P〈0．05）。结论随着体重超重或肥胖程度增加，OSAS发生的可能性增加，鼾声会随之加大，AHI和呼吸暂停低通气累积时间都随之增高，应当引起研究者们的重视。

Objective To investigate the association of apnea-hypopnea indices with body mass index （BMI） in patients with obstructive sleep apnea syndrome （OSAS）. Method 57 cases of OSAS patients diagnosed by portable polysomonograph was recruited and divided into three groups according their BMI （ BMI≤23.9,24 -27.9,≥28 respectively）. Data was analyzed by t-test with SPSS 12. 0. Results Correlation analysis indicated that the association of AHI and snoring scale with BMI was statistically significant, while similar association was not found between BMI and other indices. Inter-group comparison indicated that the three groups had significant difference in almost all the indices studied （ P 〈 0. 05 ） except AHI （ P 〉 0. 05 ）. Conclusion The significant association between BMI and AHI indicated that as weight increases, the possibility of OSAS increases, although the weight is not the only reason that aggravates OSAS. With the increase of BMI, snoring scale increases, as well as AHI, cumulative apnea-hypopnea time. The indices mentioned above are of great importance when considering the treatment of OSAS.