期刊文献+

激素替代疗法对乳腺密度的影响

原文传递
导出
摘要 目的运用乳腺X线钼钯检查技术评估绝经期妇女应用激素替代疗法(HRT)后对乳腺密度的影响。方法136例未接受过激素替代疗法的绝经期健康妇女,根据不同的用药方案分为雌孕激素组(A组)、利维爱组(B组)和未用药组(C组)。在用药前和用药12个月后对所有研究对象进行乳房X线钼钯摄片检查,运用Wolfe的乳腺分型方法将前后两次乳房X线钼钯片进行比较。结果A组中有6例(14.3%)的乳腺密度增高,B组中有4例(10.5%)的乳腺密度增高,A、B2组中没有出现乳腺组织退化,C组中有16例(28.6%)出现乳腺组织退化,没有出现乳腺密度增高。A组和B组中乳腺密度增高的比例高于C组(P〈0.05),A组和B组乳腺密度的增高差异无统计学意义(P〉0.05)。结论运用乳腺X线钼钯检查技术发现使用激素替代疗法后绝经期的妇女的乳腺组织密度显著增高,但密度增高的程度与激素的种类无关。
出处 《中国医师杂志》 CAS 2008年第6期848-850,共3页 Journal of Chinese Physician
  • 相关文献

参考文献10

  • 1Beral V, Banks E, Reeves G. Evidence from randomised trials on the long-term effect of hormone replacement therapy. Lancet, 2002, 360 (9337) : 942-944.
  • 2Coombs N J, Taylor R, Wilcken N, et al. Hormone replacement therapy and breast cancer risk in California. Breast J, 2005, 11(6) :410-415.
  • 3Gram IT, Bremnes Y, Ursin G, et al. Percentage density, Wolfe's and Tabar's mammographic patterns: agreement and association with risk factors for breast cancer. Breast cancer Res, 2005,7 (5) :R854-861.
  • 4曹厚德,蒋琴.乳腺X线摄影若干技术要素的研究[J].中华放射学杂志,2000,34(3):155-158. 被引量:81
  • 5Chlebowski RT, Hendrix SL, Langer RD, et al. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA, 2003,289(24) :3243-3253.
  • 6Lundstrfim E, Christow A, Kersemaekers W, et al. Effects of tibolone and continuous combined hormone replacement therapy on mammographic breast density. Am J Obstet Gynecol,2002,186(4) :717-722.
  • 7Martin C, Peck J, Pisano E, et al. Prior HRT use, ethnicity and mammographic density. Ann Epidemiol,2000,10 ( 7 ) :461-462.
  • 8Litherland JC. The effects of HRT on screening mammography. Breast, 2000,9(3) :117-124.
  • 9Beral V. Million Women Study Collaborators. Breast cancer and hormonereplacement therapy in the Million Women Study. Lancet, 2003,362 (9382) :419-427.
  • 10Kavanagh AM, Mitchell H, Giles GG. Hormone replacement therapy and accuracy of mammographic screening. Lancet, 2000,355 ( 9200 ) : 270 -274.

二级参考文献9

共引文献80

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部