早期胃癌的临床特点与病理分析

Clinical and pathological analysis of patients with early gastric cancer

目的:探讨发现早期胃癌(EGC)、评价预后及指导治疗的方法。方法:收集我院2004年1月-2006年12月手术治疗的胃癌病例资料,统计EGC检出率,并进行临床与病理分析。结果:2004年、2005年、2006年EGC分别占该院同期手术胃癌的5.26%,6.09%,11.11%。胃镜与病理检查符合率为92.73%。发病年龄高峰为50岁-59岁,男:女=1.9:1.0,症状及体征缺乏特异性。EGC主要病灶分布在胃窦,肉眼分型多为Ⅱc和Ⅲ型,直径多<2cm。病理分型以低分化腺癌为主,多数浸润黏膜层。黏膜内癌和黏膜下癌的淋巴结转移率分别为11.34%和36.36%。结论:EGC的检出率逐年增高,内镜多点活检可明显提高EGC的诊断率。

Objective： To investigate the features of patients of early gastric cancer （EGC） with surgery from 2004 to 2006 in our hospital. Methods： Collected the cases of gastric cancer with surgery from 2004 to 2006. Results： The rate of diagnosis of EGC in gastric cancer were 5.26% ,6.09% ,11.11% in 2004, 2005, and 2006 respectively. The accordant rate of endoscopy and pathology was 92.73%. The peak age of EGC was 50 to 59 years, male ：female = 1.9 ： 1. The symptom and medical examination were not so tipical. The focus of the EGC was in the gastric sinus, most of them were type Ⅱ c and Ⅲ ,and the diameter was less than 2cm. The pathological type was adenocarcinoma, invading mucous membrane. The lymphoid metastasis in mucous cancer and submucousa cancer were 11.34% and 36.36% respectively. Conclusion：The diagnostic rate of EGC increased gradually . The endoscopy and clamp at many places can obviously improve the diagnosis of EGC .