重组人表皮生长因子在角膜异物取出术后的疗效观察与护理

Efficacy and nursing of reconstructive human epidermal growth factor application after corneal foreign body removal

目的观察角膜异物取出术后重组人表皮生长因子的治疗效果。方法对148例铁质角膜异物的患者，在异物取出后随机分为两组：治疗组用重组人表皮生长因子衍生物滴眼液（rhEGF）和左氧氟沙星滴眼液点眼4次／d，对照组涂金霉素眼膏1次／晚，左氧氟沙星滴眼液点眼4次／d，观察两组的治疗效果。结果治疗组疗效优于对照组，P〈0．05。结论重组人表皮生长因子对角膜异物取出术后角膜上皮有很好的修复作用，配合完善的护理措施，对治疗角膜异物有较满意的效果。

Objective To observe the treatment efficacy of reconstructive human epidermal growth factor （rhEGF） application after corneal foreign body removal. Methods One hundred and forty-eight patients with ferric corneal foreign body removal were randomly divided into two groups. One group, treatment group, was given reconstructive human epidermal growth factor and levofloxacin ophthalmic solution topically, and the other group, control group, was given oculentum aureomycini and levofloxacin ophthalmic solution. The treatment efficacy was compared. Results The efficacy in treatment group was much better than control group. Conclusions Reconstructive human epidermal growth factor has good repair function for corneal epithelium after corneal foreign body removal. A better effect achieved with perfect nursing.