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急性淋巴细胞性白血病免疫表型及临床特点分析 被引量:2

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摘要 目的探讨急性淋巴细胞白血病(ALL)伴髓系抗原表达与临床表现及预后的关系。方法对26例ALL住院患者的免疫分型及临床资料进行回顾性分析。结果淋系抗原表达以CDl9、CD20表达最高;26例ALL中16例伴髓系抗原表达,以CDl3表达最高;骨髓像原始细胞中出现颗粒的ALL 3例均为伴髓系抗原表达。ALL患者出现肝、脾、淋巴结肿大、发热、出血点等临床症状的概率髓系抗原阳性者高于阴性者。髓系抗原表达阳性患者(My+ALL)其缓解率为55.55%,阴性患者(My-ALL)缓解率为62.50%,差异无显著性。而髓系抗原阳性患者(My+ALL)CD34表达率为(69.8±25)%,髓系抗原阴性患者(My-ALL)CD34表达率为(35.4±22)%,有显著性差异(P<0.05)。结论急性淋巴细胞性白血病的免疫分型是骨髓形态学的补充,对白血病的诊断和治疗有指导意义。
机构地区 浙江省人民医院
出处 《浙江实用医学》 2008年第3期163-165,共3页 Zhejiang Practical Medicine
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