摘要
本文测定了 NIDDM合并视网膜病变患者21例、无视网胰病变患 者19例及正常对照20例的红细胞聚集性有关参数。的果显示,NIDDM视网膜病 变组的低切全血粘度、红细胞聚集指数均显著高于无视网膜病变组及对照组(P< 0.01)。NIDDM组和合并视网膜病变组的血沉及血沉方程K值均显著高于对照组 (P<0.01)。NIDDM视网膜病变组的血浆纤维蛋白原水平及糖化血清蛋白指数 均显著高于无视网膜病变组和对照组(P<0.05,P<0.01)。NIDDM视网膜病变 组血清白蛋白及超氧化物歧化酶(SOD)均显著低于无视网膜病变组和对照组(P <0.05,P<0.01).NIDDM视网膜病变组红细胞聚集指数与血浆纤维蛋白原、 糖化血清蛋白指数呈显著正相关(r值 0.452、0.446,P<0.05).与血清SOD、白蛋 白呈显著负相关(r-0.462、-0.439,P<0.05).结果提示,NIDDM合并视网膜 病变患者上细胞聚集性增高,这种增高与血中纤维蛋白原水平增高,蛋白质非酶糖 基化增加、SOD及白蛋白水平降低有关.
The paremetnts related with erythrocyte aggregation were measured in 21 non- insulin dependent diabetic(NIDDM ) patients with diabetic retinopathy as compared with 19 NIDDM patients without retinopathy and 20 normal subjects. The blood viscosity at low shear rate(5. 76S-1) ,erythrocyte aggregation index, plasma fibrogen and non - enzyme glycosylated serum protein index of NIDDM patints with retinopathy were significantly higher than those of control subjects and NIDDM patients without retinopathy(P < 0.01). with other paremenrts ,the result suggested that erythrocyte aggregation increases in NIDDM patients with retinopathy and the increase is related with increase of fibrogen and non -enzyme glycosylated serum protein and decrease of serum superoxide dismutase and albumin.
出处
《中国血液流变学杂志》
CAS
1997年第3期12-14,共3页
Chinese Journal of Hemorheology