帕罗西汀治疗女性躯体化障碍的临床研究

A comparative study of paroxetine in the treatment of woman somatization disorder

目的:评价帕罗西汀对女性躯体化障碍患者的疗效和副反应。方法:对28例女性躯体化障碍患者随机分为帕罗西汀组和文拉法辛组治疗6周,用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、不良反应量表(TESS)评定疗效和副反应。结果:帕罗西汀与文拉法辛疗效相当,但其副反应轻,服用方便,依从性好。结论:帕罗西汀治疗女性躯体化障碍患者疗效确切,值得推广使用.

Objective：To compare the efficacy and side effects of paroxetine and venlafaxine in the treatment of woman somatization disorder.Methods：28 patients of woman somatization disorder were randomly assigned to paroxetine group and venlafaxine group for 6 weeks.Effects and side reactions were evaluated with HAMD and HAMA and TESS before and after treatment.Results：The therapeutic efficacy in paroxetine group was similar to that in ven- lafaxine.The efficacy in paroxetine group had fewer side effects,taking conveniently and a good compliance.Conclu- sion：Paroxetine is effective in the treatment of woman somatization disorde.It is worthwhile generalization and use.