摘要
2-氟-3-三氟甲基苯甲酸是一个重要的药物中间体，同时又是制备含氟液晶的一个重要化合物，对其合成方法进行了研究：以邻氟三氟甲基苯、丁基锂、二氧化碳为原料来合成，该合成方法操作简便，收率高达86．5％。
2-Fluoro-3-（trifluorin methyl）benzoic acid is an important sort of drug intermediate. And what＇s more; it is a vital compound as preparating liquid crystal with fluorine. Its synthesis way was studied. 1-Fhiom-2-（trifluorin methyl） benzene, n-C4H9Li and CO, was material in this way. Operation of this way is convenient and yield reached 86.5%.
出处
《医药化工》
2008年第7期15-16,共2页
Pharmaceutical Chemicals
关键词
2-氟-3-三氟甲基苯甲酸
含氟中间体
丁基锂
合成
2-Fluoro-3-（tritluorin methyl）benzoic Acid
Intermediate with Fluorine
n-C4H9Li
Synthesis
