期刊文献+

抗甲状腺药的进展与应用评价 被引量:5

Progress and Clinical Evaluation of the Antithyroid Drugs
下载PDF
导出
摘要 目的:评价抗甲状腺药的疗效、不良反应和进展,以供临床用药参考。方法:通过查阅近期国内、外相关文献进行总结、分析。结果与结论:对于大多数病人,特别是甲状腺不太大、青少年、妊娠或哺乳期妇女的甲亢患者,抗甲状腺药是首选的主要治疗手段。在治疗前及治疗中应密切监测患者的肝、肾功能,白细胞总数及分类,以便及时发现异常情况,给予停药或相应处理。 OBJECTIVE: To evaluate the progress, clinical efficacy and adverse reactions of antithyroid drugs for references of clinical drug use. METHODS: Recent pertinent medical literature both at home and abroad was reviewed and analyzed. RESULT & CONCLUSION: For most patients with hyperthyreosis, especially those with small thyroid, adolescents, or women at pregnancy or lactation, antithyroid drugs are preferred. Function of liver and kidney, TWBC (total white blood cells ) and its differential count should be given close monitoring to withdraw drugs or give corresponding management in case of abnormalities.
作者 田硕涵 周颖
出处 《中国医院用药评价与分析》 2008年第6期410-411,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 抗甲状腺药 进展 临床应用 Antithyroid drugs Progress Clinical use
  • 相关文献

参考文献8

  • 1Bergstrom U, Giovanetti A, Piras E, et al. Methimazole induced damage in the olfactory mucosa: effects on ultrastructure and glutathione levels [ J ]. Toxicol Pathol, 2003, 31(4) :379.
  • 2Yanai N, Shveiky D. Fetal hydrops, associated with maternal propylthiouracil exposure, reversed by intrauterine therapy [J]. Ultrasound Obstet Gynecol, 2004, 23 (2): 198.
  • 3三桥知明,于会经.抗甲状腺药与药物性肝损害[J].日本医学介绍,2006,27(6):271-273. 被引量:21
  • 4Fujieda M, Hattori M, Kurayama H, et al. Clinical features and outcomes in children with antineutrophil cytoplasmic autoantibody - positive glomerulonephritis associated with propylthiouracil treatment [ J ]. J Am Soc Nephrol , 2002, 13 (2) :437.
  • 5Winters MJ, Hurley RM, Lerenman DS. ANCA positive glomerulonephritis and lgA nephropathy in a patient on propylthiouracil [ J ] . Pediatr Nephrol, 2002,17 (4) : 257.
  • 6Sera N, Ashizawa K, Ando T, et al. Treatment with propylthiouracil is associated with appearance of anti - neutrophil cytoplasmic antibody in some patients with Graves' disease[J]. Thyroid,2000, 10(7) :595.
  • 7Gunton J E, Stiel J, Clifton - Bligh P, et al. Prevalence of positive anti - nrutrophil cytoplasmic antibody (ANCA) in patients receiving anti - thyroid medication [ J ]. Eur J Endocrinol, 2000 ,14 2 ( 6 ) :587.
  • 8路玫,荣延平,韦莉迪.他巴唑的不良反应及其防治[J].海峡药学,2006,18(2):177-179. 被引量:4

二级参考文献19

  • 1李泽发.他巴唑引起溶血性贫血1例报告[J].临床荟萃,2005,20(9):516-516. 被引量:3
  • 2马文菊.口服他巴唑引起双眼黄斑水肿1例[J].河北中西医结合杂志,1997,6(1):110-110.
  • 3谷淑枝 王毅力.口服他巴唑致严重血液病变2例[J].中国医院药学杂志,1996,16(6):270-270.
  • 4张笑双 刘占海.他巴唑引起药物性肝昏迷致死1例[J].中华消化杂志,2001,21(2):85-85.
  • 5安子元 徐新香 徐太毅.他巴唑引起肝损害的调查[J].中华医学杂志,1991,4:241-241.
  • 6rgstrom U,Giovanetti A,Piras E,et al.Methimazoleinduced damage in the olfactory mucosa:effects on ultrastructure and glutathione levels Toxicol Pathol,2003,31(4):379~387.
  • 7Bergman U,Brittebo EB.Methimazole toxicity in rodents:covalent bingding in the olfactory mucosa and detection of glial fibrillary acidic protein in the olfactory bubl Toxicol Appl Pharmacol,1999,155(2):190~200.
  • 8药物不良反应(第三版),北京:人民卫生出版社,721.
  • 9姜涛 修青.他巴唑只剥脱性皮炎1例[J].中国医院药学杂志,1998,18(10):478-478.
  • 10毕可波.他巴唑引起膜性肾病1例[J].中国医院药学杂志,2000,20(2):128-128.

共引文献23

同被引文献45

引证文献5

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部