不同药物治疗门脉高压性胃病疗效比较

The Curative Effect of Different Drugs in Patients with Portal Hypertensive Gastropathy

目的研究不同药物治疗门脉高压性胃病的疗效。方法60例门脉高压性胃病患者,按不同药物治疗分为:奥美拉唑组(观察组)30例,雷尼替丁组(对照组)30例,观察两组临床症状、胃粘膜改善、肝功能恢复情况及药物不良反应。结果观察组总有效率(93.3%)高于对照组(76.7%)(P<0.05);观察组胃粘膜改变总有效率(86.7%)高于对照组(66.7%)(P<0.05);观察组天冬氨酸氨基转移酶,白蛋白/球蛋白、总胆红素恢复明显优于对照组(P<0.05);两组患者均无严重不良反应发生。结论奥美拉唑治疗门脉高压性胃病患者的疗效优于雷尼替丁。

Objective To study the curative effect of different drugs in patients with portal hypertensive gastropathy. Methods 60 cases with portal hypertensive gastropathy （PHG） were divided into omeprazole group （observation group） 30 cases and ranitidine （control group）30 cases. The clinical symptoms, gastricmucosa, liver function and adverse drug reactions were observed. Results Total efficiency（93.3%） of observation group was higher than control group（76.7%）（P〈 0.05）; The total effective gastricmucosa change of observation group was（ 86.7% ）higher than control group （66.7%） （P 〈 0.05 ） ; Aspartate aminotransferase enzyme, albumin/globulin, total bilirubin resume were better than the control group （P〈 0.05）;Two groups had no serious adverse reactions. Conclusion The curative effect of omeprazole excells＇ ranitidine in patients with portalhypertensive gastropathy .