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氢氯噻嗪联合卡托普利治疗轻中度原发性高血压 被引量:1

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摘要 目的观察小剂量氢氯噻嗪联合卡托普利治疗轻中度原发性高血压的疗效及不良反应。方法160例轻中度高血压患者随机分为两组。两组所有患者均要求改变生活方式。对照组:CPT每次12.5~25mg,每日3次,口服。每周测一次血压,如血压未达标,逐渐增加剂量至50mg,每日3次。治疗组:在对照组的基础上,加服HCTE12.5mg,每日1次。结果(1)降压达标率:治疗组、对照组治疗4周末达标率分别为56.25%、36.25%(P<0.05);治疗12周末分别为90%、52%(P<0.01)。(2)降压有效率:治疗组、对照组治疗4周末总有效率分别为82.5%、68.75%(P<0.05);治疗12周末总有效率分别为100%、86.25%(P<0.01)。结论小剂量氢氯噻嗪联合卡托普利治疗轻中度原发性高血压疗效显著,副作用小,价格低廉,使用方便,值得推广应用。
作者 吴成涛 胡波
出处 《中国现代医生》 2008年第18期180-180,202,共2页 China Modern Doctor
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