吡唑衍生物的合成及生物活性

Synthesis and Biological Activity of Pyrazole Derivatives

以5－吡唑甲酸肼（7，8）为原料合成了4类共30种新化合物，这些化合物的结构均经1HNMR、元素分析证实，部分化合物还经过了MS、IR确证．对大部分化合物做了生物活性测试，结果表明均具有一定的杀菌和除草活性．

Thirty new pyrazole acylhydrazine derivatives containing carboxylate,sulfonylate, hydrazone and dipyrazole ketone were synthesized from the intermediate 1, 3,4-substituted-5-pyrazole carboxylic hydrazide(7,8). Their structures were confirmed by 1H NMRand elemental analysis. The preliminary biological tests showed that several compounds havesome fungicidal and herbicidal activity.