CT和MRI对室管膜下巨细胞型星形细胞瘤的诊断价值

The value of CT and MRI in the diagnosis of subependymal giant-cell astrocytoma

目的探讨CT和MRI对室管膜下巨细胞型星形细胞瘤(subependymal giant-cell astrocytoma,SEGA)的诊断价值。方法回顾性分析5例经临床病理证实为SEGA的CT和MRI表现及临床资料。结果本组全部5例SEGA均伴发结节性硬化,CT表现为室间孔或侧脑室前角类圆形略高密度结节(边界清楚,多呈明显均匀强化),室管膜下结节状钙化,脑实质错构瘤。MRI表现为室间孔或侧脑室前角类圆形结节(T1WI呈等低信号,T2WI呈稍高信号),室管膜下、皮质和皮质下多发稍长T1稍长T2病灶。结论CT和MRI相结合是SEGA的最佳影像检查方法,结合患者特征性临床表现,可作出较明确诊断。

Objective To evaluate the diagnostic value of CT and MRI on subependymal giant-cell astrocytoma （SEGA）. Methods Appearances of CT, MRI and clinical data in 5 cases with SEGA pathologically proved were analyzed retrospectively. Results All 5 cases in this group were accompanied with tuberous sclerosis. Based on CT findings, round-like nodules with slightly high density were appeared in the inter-ventricular foramen or frontal horn of lateral ventricle with clear border and uniform enhancement. The sub-ependymal node-like calcification and isoor slight hypo-density lesions were seen in cortical and subcortical areas. On MRI, SEGA lesions appeared as round-like nodes with iso-intensity on T1-weighted imaging and slightly high signal intensity on T2-weighted imaging near the inter-ventricular foramen or frontal horn of lateral ventricle. The long T1 and slight long T2 lesions were also seen in the cortical and subcortical areas. Conclusion CT and MRI is the best imaging diagnostic methods for SEGA. The correct diagnosis can be developed in this way combined with patient＇ s typical clinical manifestations.