摘要
目的:探讨大黄蟅虫丸与拉米夫定联合治疗慢性乙型肝炎活动性肝硬化的护理方法。方法:将86例慢性乙型肝炎活动性肝硬化患者随机分为实验组46例和对照组40例。对照组行常规治疗,实验组口服大黄蟅虫丸与拉米夫定治疗。观察药物不良反应,观察治疗前后肝功能及第1,3,6,12个月的血清HBV-DNA变化,做好各项护理工作。结果:实验组治疗后肝功能显著改善,血清HBV-DNA转阴率提高,与对照组比较有显著性差异(P<0.05)。结论:大黄蟅虫丸与拉米夫定联合治疗慢性乙型肝炎活动性肝硬化,配合精心的护理,效果满意,值得临床推广应用。
Objective： To explore methods of nursing care in the treatment of active cirrhosis in 46 patients with chronic hepatitis B with lamivudine combined with Dahuang Zhechong pill. Methods： Eighty six patients with active cirrhosis were divided into experiment group （ n = 46 ） and control group （ n = 40 ） randomly. Routine treatment was taken in control group and lamivudine combined with Dahuang Zhechong pill were given to the patients in experiment group. Observation was made on adverse reaction to drugs, liver function before and after treatment and the change of serum HBV - DNA in the first, third, sixth and twelfth month. Results： There were significant differences in the comparison of the improvement of liver function and the rate of negative turning of serum HBV - DNA between the two groups （ P 〈 0. 05 ）. Conclusion ： With lami- vudine combined with Dahuang Zhechong pill and careful nursing care, the satisfied curative effect can be achieved in the treatment of active cirrhosis in the patients with chronic hepatitis B.
