婴幼儿腹泻的轮状病毒感染与乳糖不耐受的研究

Investigation of infantile diarrhea with rotavirus infection and lactose intolerance

目的探讨婴幼儿腹泻患者的轮状病毒感染和乳糖不耐受及相互关系，帮助，临床鉴别诊断婴幼儿腹泻病因。方法对本院门诊及住院年龄在3岁以下555例腹泻患儿粪便均做常规检测、细菌培养、轮状病毒抗原检测、还原糖检测。结果轮状病毒肠炎409（73．7％）例，乳糖不耐受症349（62．9％）例，轮状病毒合并乳糖不耐受291例，占轮状病毒肠炎患者的71．1％。结论秋冬季婴幼儿腹泻主要病原体为轮状病毒，而轮状病毒肠炎多数有继发乳糖不耐受。

Objective To explore the correlation of infantile diarrhea with rotavirus infection and lactose intolerance and help to differentiate the cause of infantile diarrhea. Methods The stool samples of 555 children that age of under 3 years with diarrhea from our outpatients and inpatients were collected to do routine examination, bacterial culture, fecal rotavirus antigen detection and reducing sugar determination . Results There were 409 （73.7%） infants with rotavirus enteritis, 349 （62.9%） infants with lactose intolerance, 291 infants with rotavirus infection complicated with lactose intolerance that were 71.1% of the infants with rotavirus infection. Conclusions Rotavirus is the commonest pathogen of infant diarrhea in autumn and winter, and most of these patients with rotavirus enteritis have secondary lactose intolerance.