高眼压症患者中央角膜厚度的临床观察

Clinical Observation of Central Corneal Thickness in Patients with Intraocular Hypertension

目的：追踪观察高眼压症患者的预后及其与角膜厚度的关系。方法：选取30例（60眼）高眼压症患者（眼压≥21mmHg，≤35mmHg，正常视野，正常视神经乳头，无角膜水肿等病变）均为我院门诊患者，年龄12～50岁，平均27．3岁，男性40例，女性32例；跟踪观察5年。结果：30例高眼压症者，4例5年后发展为POAG，出现视野及视神经损害，平均中央角膜厚度为541．7±38．7μm，26例未发展为POAG，未出现视野及视神经损害，平均中央角膜厚度为583．6±35．7μm，两者比较（t=6．13，P〈0．01）差异有显著性。结论：出现青光眼性视功能损害的高眼压症患者中央角膜厚度值明显低于未出现青光眼性视功能损害者的中央角膜厚度。中央角膜厚度是判断高眼压症患者预后的重要指标之一。

Objective： To investigate the relationship between prognosis of intraocular hypertension and central corneal thickness. 60 eyes of 30 cases of intraocular hypertension syndrome with intraocular hypertension between 21 mmHg and 35 mmHg, normal visual field and normal optic nerve were selected. Their average age was 27.3 years old （ranged from 12 years to 50 ages）. There were 40 males and 32 females. All cases were followed up 5 years. Results： 4 of 30 cases developed into primary open angle glaucoma（POAG） with damage in visual field and optic nerve, their average central corneal thickness was 541.7 ± 38.7um, that in other 26 cases with POAG was 583.6 ± 35.7um, the diffence was significant（ t = 6.13, P 〈 0.01）. Conclusion： The intraocular hypertension syndrome with damage in glaucomatic visual dysfunction had thinner central corneal thickness, it may be an main indicator for prognosis in intraocular hypertension syndrome.