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基质金属蛋白酶及其抑制剂在心肌疾病中的研究进展 被引量:3

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摘要 心肌疾病常伴随着心肌细胞外基质成分的改变,细胞外基质合成或降解失衡是心肌疾病发病过程中重要的环节。细胞外基质的合成与降解主要与位于其间的基质金属蛋白酶及其特异性组织抑制剂的活性有关。基质金属蛋白酶可以分解细胞外基质,从而改变组织的形态结构。基质金属蛋白酶与特异性组织抑制剂之间的动态平衡与心肌疾病发病过程中心肌重构和心衰进展有重要关系。
作者 吴卉卉 陈敏
出处 《国外医学(老年医学分册)》 2008年第4期156-159,共4页 Foreign Medical Sciences(Geriatrics)
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