摘要
采用紫外分光光度法在314nm处测定盐酸雷尼替丁的含量及溶出度。盐酸雷尼替丁检测浓度在4～16μg/mL范围内与吸收度呈线性关系(r=0.9994,n=5),日内、日间精密度分别为0.88%、1.16%,平均回收率为99.59%,RSD=0.22%。该制剂制备工艺简单易行,质量检查方法准确可靠。
The content of ranitidine hydrochloride was determined by UV-spectrophotometry at the wavelength of 314 nm. The detected concentration of ranitidine hydrochloride was in linear relation to absorptivity in the range of 4-16 μg/mL （r=0. 999 4,n=5）. The intra-day and inter-day precision were 0.88% and 1.16% .The average recovery was 99. 59% （RSD=0.22%）.The preparation of technique is simple and the method for quality inspection is accurate and reliable.
出处
《河北化工》
2008年第7期38-39,56,共3页
Hebei Chemical Industry
关键词
盐酸雷尼替丁
制备
质量检查
ranitidine hydrochloride
preparation
quality inspection
