摘要
目的研究老年大白鼠脊髓运动神经细胞突触的变化，探讨衰老的形态学基础。方法用Golgi Deineka银染法研究比较青年（4～6个月龄）和老年（26～30个月龄）大白鼠脊髓腰段前角运动神经细胞胞体和近侧树突突触的形态和数目。结果老年大白鼠脊髓运动神经细胞上不规则和网形突触明显较青年大白鼠增多，并且突触密度明姓少于青年大白鼠。结论脊髓是神经系统的初级反射中枢，突触是其神经元实现其生理功能的重要结构，随着个体的衰老，突触数目和形态会发生改变，这也是机体衰老后生理机能减退的形态学基础之一。
Objective To observe the synapse changes of the neurons in medulla spinalis of young rats and aged rats, and to provide the morphological basis for the mechanism of decreasing functions in aged rats. Methods The synaptic changes of medulla spinalis neurons in young rats （4-6 months old） and in aged rats （26-30 months old） were observed with oil microscopy. Results The synaptic of aged rats decreased in number and had abnormal morphology. Conclusion The neurons and synapses of medulla spinalis in aged rats may present degenerative changes. The results provided morphological basis for decreasing of series functions in aged rats.
出处
《江西医学院学报》
CAS
2008年第3期27-28,33,共3页
Acta Academiae Medicinae Jiangxi
关键词
脊髓
突触
神经细胞
动物
实验
大鼠
medulla spinalis
synapses
neurons
animal, laboratory
rats
