合理用药国际指标的干预对门诊呼吸内科抗菌药物使用的影响

Rational Drug Use Indicators of the International Intervention for Outpatien Respiratory Medical Use of Antibacterial Drugs

目的探讨持续影响合理用药的主要因素及主动介入干预前后的影响结果。方法通过前后自身对照的试验,对门诊呼吸内科抗菌药物合理用药国际指标进行现场调查研究,采用主动干预处方医师处方行为的策略进行干预,并分成干预前、1次干预后、2次干预后、3次干预后共4个组别。数据用SPSS11.0软件进行统计分析。结果呼吸内科抗菌药物使用率、抗菌药物注射剂使用率从干预前的61.6%、19.2%分别下降至3次干预后的30%、10%(P<0.01);抗菌药物平均费用从干预前28.2元降至3次干预后的11.8元;抗菌药物联用现象消失;病人正确用药知晓率从90%上升到3次干预后的100%。结论采取的主动干预策略介入临床用药对改善合理用药实践是有效和可行的。

Objective To explore the influencing factors of rational drug usage （RDU）, and the effect after intervention on RDU. Methods A field investigation was carried out on the core indices of antibiotics in the outpatient department of respiratory of interuational RDU index by the way of comparison. Active intervention by prescribing physician prescribing practices of the intervention strategy. The investigation was carried out at four stages： before intervention, after the first intervention, after the second intervention, and after the third intervention. Data statistics was analyzed by SPSS11.0 software. Results The use of antibiotics dropped from 61.6% before intervention to 30% after third intervention. The use of injectable antibiotics dropped from 19.2% before intervention to 10% after the third intervention. Antibiotic costs dropped from 28.2 yuan before intervention to 11.8 yuan after the third intervention. Antibiotics combination dropped from 4.2% before intervention to 0% after the third intervention. Patients had correct indication knowledge increased from 90% before intervention to 100% after the third intervention. Conclusion Active involvement of drug intervention strategies to improve the rational drug usage practice is effective and feasible.