女性腺性膀胱炎临床诊疗分析（附47例报告）

A clinical analysis of 47 cases of female cystitis glandularis

目的研究女性腺性膀胱炎的临床诊断与治疗方法，观察其疗效与复发情况。方法对47例女性腺性膀胱炎患者采用经尿道电切术治疗，其中32例术后加膀胱腔内灌注治疗。随机分为三组：单纯电切组（A组，15例），另两组术后分别给予比柔比星（B组，16例）和丝裂霉素（C组，16例）腔内灌注治疗，随访1年，观察患者症状缓解情况和复发情况。结果44例患者完成随访。三组有效率分别为A组38．5％，B组87．5％，C组86．7％，B、C组与A组比较差异有统计学意义（χ^2=13．80，P〈0．01）；三组复发率分别为A组30．8％，B组0，C组13．3％，各组复发率比较差异无统计学意义（χ^2=4．86，P〉0．05）。结论 腺性膀胱炎的临床表现多样化，尿流动力学检查无特异性；采用经尿道电切加膀胱腔内灌注治疗效果好于单纯电切术治疗，复发率低。

Objective To evaluate the procedure of diagnosis and treatment for cystitis glandularis in female. Methods Forty-seven patients were classified into 3 groups randomly after being operated by transurethral resection： 15 cases without any other therapy（A group）, 16 cases with bladder instillation of pirarubicin afterward （B group）, 16 cases with bladder instillation of mitomycin afterward （C group）. Symptomatic relief and recurrence were investigated in 1-year follow-up visit. Results Forty-four cases had fulfilled the entire follow-up visit. The effective rates of the three groups were 38.5%, 87.5% and 86.7% respectively （χ^2= 13.80,P 〈 0.01 ）, the recurrence rate was 30.8%, 0, 13.3% respectively （χ^2 = 4.86,P 〉 0.05 ）. Conclusions The clinical situation of cystitis glandularis has no specificity. Cystisis glandularis has diversification of the clinical symptoms, uredynamics. Transurethral resection with bladder instillation is more effective than transurethral resection simply, the recurrence rate is lower.