苦豆子种子生物碱成分研究

Alkaloids in Sophora alopecuroides Seed and Relevant Tests for Activity

从苦豆子种子中分得７种生物碱，分别鉴定为氧化苦参碱，氧化槐果碱、金雀花碱、苦参碱、槐果碱、槐定碱和尼古丁，尼古丁为首次从该属植物中得到，并对提取物及生物碱进行了体外活性测试。

J Houghton and S Jackson(Department of Pharmacy,Kings College London,London SW3 6LX)P R Twentyman(MRC Clinical Oncology and Radiotherapeutics Unit,Cambridge CB2 2QH)Abstrat Seven alkaloids were isolated from the seed of Sophora alopecuroides and identified to be oxymatrin,oxysophocarpine,cytisine,matrine,sophocarpine,sophoridine and nicotine respectively by comparing chromactographic and spectral characteristics with authentic known compounds.Nicotine was isolated from Sophora for the first time. The activity of extracts and alkaloids against cancer,virus,dermatophytes and bacteria was carried out in vitro.