三种镇痛方法在人工流产术中的临床对比研究

A Comparsion Study on Three Different Analgesic Methods in Induced Abortion

目的:探讨人工流产中最佳镇痛方法。方法:将320例自愿行人工流产的早孕妇女随机分为A组(口服米索前列醇)、B组(丙泊酚注射)、C组(米索前列醇联合丙泊酚)、D组(常规人工流产),每组80例。对四组镇痛效果、宫颈松弛情况、术中出血量、子宫收缩幅度、手术时间、人工流产综合症及呼吸、循环系统情况进行比较。结果:A、B、C组镇痛、扩宮效果、手术时间与D组比较均有显著性差异(P(0.01),尤以C组效果最佳。子宫出血量及子宫收缩幅度四组无显著性差异(P(0.05)。应用米索前列醇后麻醉药物用量减少(P(0.05),术中副反应少(P(0.05)。结论:米索前列醇联合丙泊酚用于无痛人工流产,镇痛效果及宫颈松弛良好,副反应少且操作简单安全,值得临床推广使用。

Objective： To study the best antalgic methods in induced abortion. Methods：320 women with early pregnancy who asked for induced abortion were divided into four groups randomly. Women in group A were given 0.4mg misoprostol,women in group B were injected propofol into vein, women in group C were given misopostol and propofol , but women in group D were given nothing, every group was 80 cases. The degree of pain, the degree of cervical tab, amount of bleeding during the operation , the retractile extent of uterus, the operative time and side - effect were observed in four groups respectively. Results： The pain relief effect, the degree of cervical tab, the operative time , group A, B, C showed significant difference com- pared with group D ,respectively（ P 〈0.01 ） ,and the best one was the group C . but amount of bleeding and the retractile extent of uterus showed no significant difference among the four groups （ P 〉0. 05）. the quantity of dope and the incidence, group C showed significant difference compared group B （ P 〈 0.05 ）. Conclusion ： Misoprostol combined with propofol is an effective way in inducing abortion. Its pain relief effectiveness and the degree of cervical tab are more positive than the others . It has less incidence and the operation is simple and safe, So, It is suitable for wide-spread use.