阳春市2003～2007年围产儿出生缺陷监测分析

Analyzing the Monitoring of Perinatal Birth Defect from 2003 to 2007 in Yangchun

目的：通过回顾分析我市两间监测医院出生缺陷的消长情况,了解阳春市出生缺陷的高危因素,及时发现可疑的致畸因素及产前诊断的不足和需要强化之处,为开展出生缺陷的预防、早期诊断和干预提供依据。方法：依照《中国出生缺陷监测方案》,对2003～2007年在人民医院和保健院分娩的产妇及其围产儿的资料进行统计和分析。结果：5年共监测围产儿14229例,缺陷儿225例,发生率为15.81‰,主要出生缺陷为胎儿水肿综合征、总唇腭裂、先天心、神经管畸形、脑积水、多指（趾）,马蹄足内翻、尿道下裂等;男婴出生缺陷发生率较女婴显著增加。结论：孕前及孕早期预防和加强产前诊断,可减少新生儿出生缺陷的发生,颜面部、手足部、心血管等系统的B超检查技术有待加强,孕中期B超检查列入产前检查常规内容。

Objective： Retrospective analysis of the birth defects of two hospitals in Yangchun region , in understanding the risk factors , timely detection of suspicious teratogenic factors and the lack of prenatal diagnosis and the need to strengthen the local, provide a sufficient basis for the purpose of newborn birth defects prevention, early diagnosis and intervention. Methods： In accordance with the “China Population Birth Defects Monitoring Programme”, delivery of maternal and perinatal statistics and data analysis were done , which from The People＇s Hospital and The Maternity and Child Health Hospital in YangChun City in 2003 2007 . Results ：A total of 14,229 cases of perinatal monitoring in 5 years, 225 cases of infant defects,which the rate was 15.81 ‰, major birth defects were Schridde syndrome, cheilopalatognathus, congenital heart disease, terato-neurocanal , hydrencephal, hyperdactylism, congenital talipes equinovarus and hypospadias; incidence of birth defects in boys was remarkably increased than that in girls. Conclusion：The occurrence of birth defects could be reduced in accordence with Pre-pregnancy and pregnancy prevention and the strengthening of early prenatal diagnosis, B-type ultrasonic inspection techniques of facial, pedicure, manicure department, cardiovascular and other systems need to be strengthened, B - mode ultrasound examination should be included in routine prenatal examination in Second Trimester.