比索洛尔联合吲达帕胺治疗扩张型心肌病效果观察

Bidptolol comfined with indapamide in Treatify Dilated condiomyopathy

目的:探讨比索洛尔联合吲达帕胺对改善扩张型心肌病左心室功能的作用。方法:选择确诊的86例扩张性心肌病,随机分为比索洛尔、吲达帕胺治疗组与对照组。对照组予强心、扩张血管等常规治疗,治疗组在常规治疗的基础上,加用比索洛尔及吲达帕胺,观察1年,比较两组治疗前后心率、血压、左心室内径的变化,评估其临床治疗的有效性。结果:治疗组、对照组心率、血压均下降,左心室内径缩小、心功能改善程度不同,两组比较差异具有非常显著的统计学意义(P<0.001)。结论:比索洛尔联合吲达帕胺在常规抗心力衰竭药物治疗的基础上,可明显改善患者的心功能,缩小左心室内径,提高患者的生存率,是值得临床推广的治疗方法。

Objective：To investigate the application of Bisprolol and Indapamide in the improvement of the left ventricular function of dilated cardiomyopathy patients. Methods ：86 cases of dilated cardiomyopathy patients all with varying degrees of heart failure were selected and then divided into Bisprolol,Indapamide group and the control group randomly. Bisprolol and Indapamide was added to the therapy of the treatment group on the basis of the conventional application of cardiac-vascular treatment. Observe it for one year and compare The changes of patients＇ clinical indicators such as heart beat rate, blood pressure and left ventricular diameter changes before and after the treatment were observed and compared for one year to assess the clinical effectiveness and safety. Resuits： The heart functions of the treatment group showed significant improvement compared with that of the control group and there was a significant difference between the two groups （P 〈 0. 001 ）. Conclusion：On the basis of the conventional application of cardiac-vascular treatment Bisprolol combined with Indapamide can significantly improve the heart functions,shorten the left ventricular diameter and enhance the survival rate of the patients. So it is highly recommended.