红细胞门冬氨酸转氨酶活性系数评价实验性维生素B_6缺乏

TX STUDY ON THE ACTIVATION COEFFICIENTS OF ERYTHROCYTE ASPARTATE AMINO TRANSFERASE IN EVALUATION OF EXPERIMENTAL VITAMIN B 6 DEFICIENCY

通过对小鼠Ｂ６不同含量的饲料（缺乏、充裕、普通）的喂养，证实了红细胞内门冬氨酸转氨酶（ＥＡＳＴ）的活性系数（ＡＣ）与小鼠维生素Ｂ６缺乏密切相关，当小鼠缺乏维生素Ｂ６一周时，ＡＣ值迅速提高。提出ＡＣ值＞１．８时，可认为是维生素Ｂ６缺乏。该法测定ＥＡＳＴ的ＡＣ值的变异系数为２．９３～３．８９％，方法简便，重现性好。

From a study of mice fed on stock diet, vitamin B 6 defecient and supplemented diets we found that the activation coefficients (AC) of erythrocyte aspartate aminotransferase (EAST) with various status of vitamin B 6 was closely related. After one week deficiency of vitamin B 6 the AC values were elevated. We think that the AC values>1.8 can be defined as vatamin B 6 deficiency. But more precise evaluation standands are still to be set up. Coefficient of variation of EAST AC values is 2.93%—3.89%. The method is simple and easy to carry out in practice.