鹿根的研究进展

Progress in studies of Rhaponticum carthamoides

目的对鹿根的生态学、化学成分、药理活性研究进展进行综述。方法参考近30年国内外40余篇文献,简述其生态学相关内容,按照化合物的结构类型对其化学成分进行分类,对其药理作用进行总结。结果鹿根为一类喜阳植物,对环境有较好的适应性;含有多种化学成分,主要含有黄酮类,甾体类,三萜皂苷类,酚酸类,挥发油和多糖等化合物;具有促细胞生长、降血脂、抗动脉粥样硬化、抑菌、增强免疫系统、强壮机体、调节抗应激等药理作用。结论目前对鹿根在化学成分和药理活性方面的研究较多,关于其临床应用和作用机制尚有待于更深入的研究。

Objective To review the studies on biological characteristics, chemical constituents, pharmacological effects of Rhaponticum carthamoides. Methods On the basis of more than 40 published literatures within 30 years, the biological characteristics of Rhaponticum carthamoides were briefly reviewed. The chemical constituents were classified according to their structural types; their pharmacological effects were also summarized. Results The Rhaponticum carthamoides was a light-favored plant with good adaptability to light conditions, and it contained many kinds of chemical constituents, primarily flavonoids, phytoecdysteroids, triterpenoids, phenolic acids, essential oil and polysaccharides etc. It had been proved that Rhaponticum carthamoides processed the cell-growth promoting, hypolipidemic, antiatherosclerotic, antimicrobial, antitumot, immunotropic, tonic, and anti-stress regulation effects. Conclusions Many studies have been performed on the chemical constituents and pharmacological actions of Rhaponticum carthamoides so far, and further researches on biological activities and its mechanism are to be continued.