冠心病患者C-反应蛋白与血脂联合检测200例分析

Analysis on Combination Detection of C-reaction Protein and Lipid of CHD

目的探讨冠心病患者血清CRP与血脂联合检测的临床应用价值。方法用美国BECK-MAN360CE全自动免疫特种蛋白分析仪检测150例健康人和200例冠心病患者血清中CRP和TG、TC、HDL-C、LDL-C水平。结果冠心病组血清CRP、TG、TC和LDL-C明显高于健康对照组,差异有统计学意义(P<0.05),且CRP与TG、TC、LDL-C呈正相关,病例组血清HDL-C水平明显低于对照组,差异有统计学意义(P<0.05),且CRP与HDL-C呈负相关。结论CRP是心血管疾病的独立危险因素,冠心病患者CRP与血脂代谢异常有相关性;与血脂联合检测对冠心病的诊断和治疗有重要意义。

Objective To discuss the clinical application value of combination detection of CRP and lipid for CHD. Methods The 150 cases of healthy adult and 200 cases of CHD were detected in their serum CRP, TG, TC, HDL- C and LDL- C with the auto- analyzer of BECK- MAN360CE. Results The CRP, TG, TC, and LDL- C in CHD group was obviously higher than that in healthy group and in positive relationship with P 〈 0.05. The HDL- C in CHD group was lower than that in control group P 〈 0.05. The CRP had negative relationship with HDL - C. Conclusion The CRP might be an isolate risk factor of cardiovascular disease. The CRP has relationship with abnormal of lipid. The combination detection might helpful to diagnose and treat CHD.