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静脉应用胺碘酮治疗阵发性房颤36例疗效观察 被引量:1

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摘要 目的观察静脉应用胺碘酮治疗阵发性房颤的临床疗效。方法将68例阵发性房颤病人随机分为治疗组和对照组,治疗组静脉应用胺碘酮150mg加入生理盐水稀释,于10min静脉注入。转复窦性心律后静脉维持(600μg/min),同时口服胺碘酮,每周5d。第1周600mg/d,第2周400mg/d,第3周200mg/d。对照组用普罗帕酮70mg,加入5%葡萄糖液稀释,5min^10min静脉注入。转复窦性心律后次日口服普罗帕酮200mg,8h口服1次,一周后逐渐减量至150mg/d维持。观察两组转复窦性心律的有效率、不良反应及维持率。结果治疗组转复率为86%,维持率为81%;对照组转复率为84%,维持率为56%。结论胺碘酮与普罗帕酮均可静脉应用于转复阵发性房颤。但胺碘酮在维持窦性心律方面较普罗帕酮更为有效。
出处 《中西医结合心脑血管病杂志》 2008年第7期850-851,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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