模拟移动床色谱法分离C_(60)的条件选择

Condition selection of C_(60) separation with simulated moving bed chromatography

用模拟移动床色谱对C60进行了分离。工作参数:直径1 cm长10 cm的半制备柱;固定相为ODS;残余液流速2.2 mL/min,萃取液流速2 mL/min,进样流速12 mL/h;室温;切除C60前杂质的流动相V(甲醇)∶V(甲苯)=60∶40,切换时间14.5-15.5 min;切除C60后杂质的流动相V(甲醇)∶V(甲苯)=50∶50,切换时间19.5-20.5 min;在上述条件下,对80%C60固体粉末进行分离,C60的纯度可达95%,收率大于70%。结果表明,这种方法是可行的,易于实现工业化。

C60 was separated by using simulated moving bed chromatography. The work parameters were as follows： 1 × 10 cm half preparation column;ODS as station phase;flow speed of remain liquid：2.2 mL/min; flow speed of extraticon liquid：2 mL/min;flow speed of injecting sample： 12 mL/h;room temperature;moving phase of before-impurities of C60V （methanol） ： V （toluene） = 60：40 C60, swtich time： 14.5 - 15.5 min;moving phase of after-impurities of C60 V （methanol）： V （toluene） = 50：50;switch time： 19.5 -20.5 rain, 80 % C60 solid powder was separated. C60 purity was more than 95 % and its yield was over 70 %. The results show that this method is feasible, which can easily realize industrialization.