摘要
目的观察术前应用盐酸戊乙奎醚注射液（长托宁）后，异丙酚无痛人工流产术不良反应的发生情况。方法将100例早孕患者随机分为A组、B组，每组50例（n=50）。两组均静脉注射芬太尼（1μg／kg）和异丙酚（2．0mg／kg）后开始手术，术中必要时每次追加20—50mg。A组无术前用药，B组术前应用长托宁肌内注射，观察血压、心率（Hn）变化及其他不良反应。结果与A组比较，B组诱导2min后的学压、HR高（P〈0．05），无明显抑制。B组患者恶心及呛咳发生率低。结论异丙酚无痛人工流产术前给予长托宁肌内注射，能有效抑制麻醉中不良反应的发生，并且操作方便，可常规应用。
Objective To explore the underlying mechanism in which penehyclidine mitigates the side - effects of propofol and fentanyl and prevent induced abortion syndrome and postoperative bellyache. Methods 100 pregnant volunteers with the gestational period of 40 to 80 days were divided into contyol and observation groups. Penehyclidine was used in observation group but not in contyol group to compaye the incidence of induced abortion syndrome and the postoperative analgestic effect between the two groups. Results Penehyclidine has been found to effectively prevent induced abortion syndrome and reduce postoperative bellyache. Conclusion penehyclidine is favored because it can effectively impede respiration and circulation suppression caused by propofol and fentanyl , and thereupon enhances the fafety of the operation.
出处
《临床和实验医学杂志》
2008年第7期79-79,81,共2页
Journal of Clinical and Experimental Medicine
关键词
长托宁
无痛人工流产
不良反应
Painless induced abortion
Induced abortion syndrome
Penehyclidine
