OSAHS患者上气道磁共振影像研究

Study of upper airway image with MRI in obstructive sleep apnea hypopnea syndrome

目的:研究清醒状态下阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者与正常健康人在磁共振(MRI)上的上气道参数差异和阻塞平面情况。方法:OSAHS患者和正常健康人各20例,进行MRI检查和测量。结果:①.OSAHS组RP区,RG区气道截面积明显小于对照组(p<0.01);②.OSAHS组RP区、RG区、EPG区气道前后径/左右径(AP/LR)比值均明显大于对照组(p<0.05);③.OSAHS组RP区、RG区、EPG区咽侧壁厚度均明显大于对照组(p<0.05);RG区,EPG区咽后壁厚度明显大于对照组(p<0.01);④.OSAHS组软腭长度、厚度和截面积均明显大于对照组(p<0.05);⑤.95%的OSAHS患者在清醒状态下即可见上气道阻塞平面。70%的OSAHS患者为多平面阻塞,阻塞多发生于软腭后区。结论:OSAHS患者上气道参数与正常健康人有显著性差异。软腭后区是OSAHS患者上气道最狭窄的部位。

Objective： To investigate the differences of upper airway indices and locate the site （s） of obstruction in obstructive sleep apnea hypopnea syndrome （OSAHS） with magnetic resonance image （MRI）. Method： 40 subjects, in which 20 subjects diagnosed as OSAHS polysomnographically as a experimental group, and 20 nonsnoring age-sex matched normal subjects as a control group, were used in this study. MRI was taken for the patients with OSAHS and those in control. Result： In OSAHS group, the AP/LR ratio and the thickness of lateral pharyngeal wall in RP, RG, EPG regions, the length, thickness and cross-sectional area of the soft palate were statistically larger than those of the control group （p〈0.05）. The cross-sectional area of RP and RG regions were statistically smaller than that of the control group （p〈0.01）. The thickness of posterior pharyngeal wall in RG and EPG regions was statistically larger than that of the control group （p〈0.01）. Obstructive site （s） existed in 95% awake OSAHS patients and multiple sites in 70%. Velopharyngeal region was the most narrow site of upper airway in OSAHS patients. Conclusion： Velopharyngeal region was the most narrow site of upper airway in OSAHS patients.