101例肺癌患者血清肿瘤相关抗原Scc-Ag检测结果分析

Analysis of serum tumor specific antigen Scc-Ag results in 101 patients with pulmonary carcinoma

目的:评价血清肿瘤相关抗原Scc-Ag的水平测定对肺癌的临床诊断价值。方法:采用化学发光微粒子免疫分析技术检测101例肺癌、65例肺良性疾病、38例正常对照者血清Scc-Ag的水平。结果:肺鳞癌患者血清Scc-Ag水平明显高于其他各组,差异显著(P<0.05);肺鳞癌临床分期越晚,其Scc-Ag水平与阳性率越高。结论:血清Scc-Ag的检测可提高对肺鳞癌的诊断,对肺鳞癌病情判断及预后有较大帮助,但对肺鳞癌早期诊断意义不大。

Objective： To evaluate the diagnostic value of serum tumor specific antigen Scc - Ag for pulmonary carcinoma. Methods ：The level of Scc -Ag was measured in 101 patients with pulmonary carcinoma, 65 patients with benign disease of lung and 38 healthy individuals by Chemiluminescence immunoassay. Results： The level of Scc - Ag was significant high in patients with squamous cell carcinoma of lung （P 〈 0. 05 ）. And the level and positive rate of Scc - Ag will be increased with the development of squamous cell carcinoma of lung. Conclusion：The study suggests Scc - Ag test is useful for squamous cell carcinoma of lung, and is also helpful for judgment of course and prognosis, but not for its early diagnosis.