正交试验优选非粘栓的提取工艺

Optimizing Extracting Process of Unsticking Epistomium (非粘栓) by Orthogonal Experiment

目的:用正交设计法对非粘栓药物的提取工艺进行优选。方法:以浸膏得率、柚皮苷含量作为考察指标,实验选择加水量、浸泡时间、煎煮时间,煎煮次数等对水提取影响较大的四个因素,每个因素取三个水平。结果:8倍量的水煎煮三次,每次1小时,不用浸泡,柚皮苷提取率高。结论:该工艺合理可行,稳定可靠。

Objective： To optimize the extracting process of unsticking epistomium by orthogonal experiment. Method： Extracta sicca yield and naringin cont. was as examining index to test the main factors such as selecting imbitition amount, dousing time, decocting time and decocting number of times which could influence the extraction more effectively. Each factor included three levels. Result： The extraction percentage of naringin was high in the condition of extracting three times with 8 volumes of water （ not for soaking） for one hour each time. Conclusion： The optimized process is reliable, stable and available.