转基因在动物生产中的应用

Applications of Transgenic Technology in Animal Production

人们一直期望畜产品和人类健康产品能快速得到提高,DNA重组技术和转基因的出现使得在不同物种间,甚至不同系统发育领域间的这一提高在很大范围内变为可能。如今,我们能在细菌中生产人类胰岛素,在牛奶中获得人类凝结因子。转基因、动物克隆和动物多产技术的进步在一定程度上已经实现了在动物转基因领域的期望。作者回顾了当前动物转基因乳、肉和转基因抗病动物的研究近况,并讨论了一些由转基因技术应用而引发的生物伦理学和商业性问题。

There is a constant expectation for fast improvement of livestock production and human health care products.The advent of DNA recombinant technology and the possibility of gene transfer between organisms of distinct species,or even distinct phylogenic kingdoms,has opened a wide range of possibilities.Nowadays we can produce human insulin in bacteria or human coagulation factors in cattle milk.The recent advances in gene transfer,animal cloning,and assisted reproductive techniques have partly fulfilled the expectation in the field of livestock transgenesis.This paper reviews the recent livestock transgenesis in the field of pharmacology,meat and dairy industry.Finally,some bioethical and commercial concerns raised by the transgenesis applications are discussed.