期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

动物多聚免疫球蛋白受体研究概况 被引量：2

Research Overview on Animal Polymeric Immunoglobulin Receptor
下载PDF
导出
摘要 多聚免疫球蛋白受体(polymeric immunoglobulin receptor,pIgR)是主要组织相容性复合物(MHC)家族中的重要成员,是分泌性免疫系统(SIS)的重要组成成分,在IgA/IgM的转运和黏膜免疫中发挥着重要的作用。作者结合近年来的研究综述了pIgR的分子结构、生物学功能和研究概况。 Polymeric immunoglobulin receptor（abbreviation as pIgR） is the key member of major histocompatibility complex（MHC） and secretory immune system（SIS）.It plays an important role in IgA or IgM transportation and mucosa immune.This article summarizes the molecular structures,biological functions and research advances of pIgR based on recent researches.
作者 张春刚 王加启 刘光磊 程金波 卜登攀 赵国琦
机构地区 中国农业科学院北京畜牧兽医研究所动物营养学国家重点实验室 扬州大学动物科学与技术学院
出处 《中国畜牧兽医》 CAS 2008年第7期49-51,共3页 China Animal Husbandry & Veterinary Medicine
基金 国家科技支撑计划(2006BAD04A03) 国际合作项目(2006DFB32160) 中国农业科学院北京畜牧兽医研究所青年基金
关键词 pIgR/SC IgA/IgM 抗体转运 黏膜免疫 pIgR/SC IgA/IgM antibody transportation mucosa immune
分类号 Q512.2 [生物学—生物化学]
  • 相关文献

参考文献18

  • 1Brandtzaeg P. Role of secretory antibodies in the defence against infections[J]. Int J Med Microbiol, 2003, 293 : 3-15.
  • 2Gurevich P, Zusman I, Moldavsky M, et al. Secretory immune system in human intrauterine development: immunopathomorphological analysis of the role of secretory component(pIgR/SC)in immunoglobulin transport (review)[J]. Int J Mol Med, 2003, 12:289-297.
  • 3Groot N D, Kuik-Romeijn P V, Lee S H, et al. Increased immunoglobulin A levels in milk by over-expressing the routine polymeric immunoglobulin receptor gene in the mammary gland epithelial cells of transgenic mice[J]. Immunology, 2000, 101:218-224.
  • 4Groot N D, Kuik-Romeijn P V, Lee S H, et al. Over-expression of the murine pIgR gene in the mammary gland of transgenic mice influences the milk composition and reduces its nutritional value [J]. TransgenRes, 2001, 10:285-291.
  • 5Hamuro K, Suetake H, Saha N R, et al. A teleost polymeric Ig receptor exhibiting two Ig-like domains transports tetrameric IgM into the skin[J]. J Immunol, 2007, 178:5682-5689.
  • 6Krajci P, Kvale D, Tasken K, et al. Molecular cloning and exonintron mapping of the gene encoding human transmembrane secretory component(the poly-Ig receptor)[J]. Eur J Immunol, 1992, 22:2309-2315.
  • 7Kulseth M A, Toldo S S, Fries R, et al. Chromosomal localization and detection of DNA polymorphisms in the bovine polymeric immunoglobulin receptor gene[J]. Anim Genet, 1994, 25 : 113-117.
  • 8Kulseth M A, Krajci P, Myklebost O, et al. Cloning and characterization of two forms of bovine polymeric immunoglobulin receptor cDNA[J]. DNA Cell Biol, 1995, 14:251-256.
  • 9Kumura B H, Sone T, Shimazaki K, et al. Sequence analysis of porcine polymeric immunoglobulin receptor from mammary epithelial cells present in colostrums[J]. J Dairy Res, 2000, 67 : 631-636.
  • 10Monteiro R C , Winkel J G. IgA Fc receptors[J]. Annu Rev Immunol, 2003, 21:177-204.

同被引文献36

  • 1唐庆娟,戚欣,耿美玉.多聚免疫球蛋白受体(pIgR)在粘膜免疫中的重要功能[J].中国生物化学与分子生物学报,2007,23(9):724-729. 被引量：17
  • 2Tariku Markos Tadiso,Animesh Sharma,Ivar Hordvik.Analysis of polymeric immunoglobulin receptor- and CD300-like molecules from Atlantic salmon[J].Molecular Immunology.2011(3)
  • 3J.H.W.M. Rombout,S.J.L. van der Tuin,G. Yang,N. Schopman,A. Mroczek,T. Hermsen,J.J. Taverne-Thiele.Expression of the polymeric Immunoglobulin Receptor (pIgR) in mucosal tissues of common carp ( Cyprinus carpio L.)[J].Fish and Shellfish Immunology.2008(5)
  • 4Qiang Li,Wenbin Zhan,Jing Xing,Xiuzhen Sheng.Production, characterisation and applicability of monoclonal antibodies to immunoglobulin of Japanese flounder ( Paralichthys olivaceus )[J].Fish and Shellfish Immunology.2007(5)
  • 5Per Brandtzaeg.Role of secretory antibodies in the defence against infections[J].International Journal of Medical Microbiology.2003(1)
  • 6Gurevich, P. , I. Zusman, M. Moldavsky, et al. , Secretory immune system in human intrauterine development: immune pathomor phological analysis of the role of secretory component (pIgR/SC) in immunoglobulin transport (review)[J]. International journal of molecular medicine, 2003, 12(3): 289-297.
  • 7Kaetzel, C. S. , The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces[J]. Im- munological reviews, 2005, 206: 83-99.
  • 8Braathen, R. , V. S. Hohman, P. Brandzaeg, etal. , Secretory antibody formation: conserved binding interactions between J chain and polymeric Ig receptor from humans and amphibians[J]. Journal of Immunology, 2007, 178(3) : 1589-1597.
  • 9Hamuro, K. , H. Suetake, N. R. Saha, etal. , A teleost polymeric Ig receptor exhibiting two Ig-like domains transports tetrameric IgMinto the skin[J]. Journal of Immunology, 2007, 178: 5682-5686.
  • 10Krajci, P. , R. Solberg, M. Sandberg, et al. , Molecular cloning of the human transmembrane secretory component (poly-Ig recep- tor) and its mRNA expression in human tissues[J]. Biochemical and Biophysical Research Communications, 1989, 158: 783-789.

引证文献2

二级引证文献1

中国畜牧兽医
2008年 第7期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部