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深部真菌感染及其耐药性分析 被引量:2

DEEP FUNGAL INFECTION AND DRUG RESISTANCE ANALYSIS
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摘要 目的了解深部真菌感染现状及其耐药性,为临床深部真菌感染提出防治措施。方法采用细菌分离培养和药敏试验方法进行了观察。结果从51369份临床标本中共分离真菌1435株,检出率为10.4%;分离真菌15种,白色念珠菌仍为主要菌种。各种真菌对6种抗真菌药物均出现了不同程度的耐药。结论真菌感染在临床上呈上升趋势且产生了耐药菌株,真菌对两性霉素、制霉菌素、5-氟胞嘧啶仍保持较高的敏感性。 Objective To know the deep fungal infections and drug resistance in order to propose measures for prevention and control of clinical deep fungal infections. Methods The methods of bacterial isolation and culture and drug sensitivity test were used for observation. Results A total of 1435 strains of fungi were isolated from 51369 clinical specimens, with an isolation rate of 10-4%. Fifteen species of fungi were identified. Candida albicans was still the main one. Each species was found to be resistant to 6 antifungals to various degrees~ Conclusions Fungal infections tend to increase and the anti- fungal- resistant strains were found from time to time. The fungi still have high degree of susceptibility to amphotericin B, nystatin and 5 - fluorouracil.
作者 王宇川
出处 《中国消毒学杂志》 CAS 北大核心 2008年第4期402-404,共3页 Chinese Journal of Disinfection
关键词 真菌感染 耐药性 调查 fungus infection drug -resistance survey
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