三种人体数据集的腓骨瓣三维可视化应用研究

Application of 3D visualization models of fibular flap developed by three human digital datasets

目的研究三种人体数据集的腓骨瓣三维可视化应用。方法①健康自愿者2人，经肘静脉注射造影剂，使用64排多层螺旋CT进行双下肢扫描，观察腓动脉及其分支分布及彼此间的吻合情况，将下肢二维灰度．DICOM格式图像以三维体数据的形式输入计算机，应用Amira4.1软件对腓动脉及腓骨的结构进行三维重建并立体显示。②取新鲜捐献尸体1具，采用改良的明胶-氧化铅灌注术经腹主动脉灌注，灌注后对双下肢行连续螺旋CT扫描，观察腓动脉及其分支的分布情况。利用Amira4．1软件对腓动脉及其分支结构进行三维重建并立体显示。③应用“虚拟中国人”（VCH）男性3号数据集，在薄层断面图像上观察小腿主要解剖结构，应用Amira4．1软件对小腿主要结构进行计算机三维重建并立体显示。结果运用Amira4．1图像处理软件，在三维表面重建的图像中可清晰地观察到外科腓骨瓣各解剖结构的形态，特别是腓动脉的分支情况和体表的投影得到很好的显示。利用软件的Movie Maker模板创建电影文件，将其制作为电影，画面清晰流畅，可直观、立体地显示形态特征。结论三种数据集重建的图像可以提供正常腓骨瓣三维动态解剖，对腓骨瓣的临床试验、基础研究、临床训练和手术规划具有重要应用价值。

Objective To explore application of the 3D visualization models of fibular flap developed by 3 human digital datasets. Methods First, 2 adult volunteers underwent contrast-enhance CT angiography of lower limbs using a 64-row multi-slice spiral CT after injection of Uhravist （3.5ml/s） through the median cubital vein. The 2D images from the scanning in DICOM format were transformed into three-dimensional data by computer. The structures of fibular flap were observed and digital visualization models of fibular flap were established by three-dimensional computerized reconstruction out of these data using Amira 4.1 software. Secondly, 1 fresh adult cadaver specimen was infused with modified leadoxide-gelatine mixture by abdominal aorta to be subjected to spiral CT scanning over both lower limbs. The cross-sectional images obtained from the CT scanning were reviewed to study structures of fibula flap on a section-by-section basis. 3D computerized reconstructions of fibula flap were conducted using cadaveric data and Amira 4.1 software. Thirdly, the cross-sectional images of fresh tissues from the Virtual Chinese Human （VCH） Male 3 dataset were reviewed, and the leg structures were studied on a section-by-section basis. 3D computerized reconstructions of fibular flap were conducted using the dataset and Amira 4. 1 imaging software. Results The three-dimensional images could perfectly display the main and adjacent structures of fibular flap after treatment by software Amira 4.1, distribution of fibular artery and projection of body surface in particular. Film documents produced by MovieMaker module could be transformed into movies with distinct and fluent pictures which displayed directly and stereoscopically the morphologic characteristics of fibular flap. Conclusion Since 3D visualization models of fibular flap developed by 3 human digital datasets can offer section by section insights into the anatomy of the interested structure, they are valuable in clinical experiment, basic research, clinical training and surgical planning.