食管癌及癌前患者血清锌含量变化动态分析

A study of the dynamic change of the zinc contents in the serum of the patients with various precacinoma

用原子吸收分光光度法测定食管癌高发区鹤壁市郊的癌症患者及癌前各期人群血清锌含量。结果表明,食管癌高发区食管上皮细胞处于正常,轻度增生、重度增生、近癌和癌变的不同人群、随着食管癌变的进展,血清锌水平(分别为:15.93±2.36,15.57±2.55、14.65±2.10、11.79±2.01.13.28±2.10μmol?L)有逐渐降低的趋势,以癌症组血清锌水平的降低为最明显。结果提示食管癌病人血清锌低很可能是癌变后继发性改变而引起。

In this study. the zinc contents in the serum of the patients with esophagealcancer or various precarcinoma in the high--incidence area were determinedwith a flame of atomic absorption spectrophotometer. The results showedthat the zinc levels in the serum in various cases of normal, hyperplasia, severedysplasia, near-carcinoma and carcinoma of esophageal epithelium decreased gra-dually. The results suggest that hypozincemia in patients with esophageal cancerbe a secondary event.